University of Pittsburgh | Department of Psychiatry

about the lab:

The ultimate goal of the Mood and Individual Differences Lab is to develop more effective, personalized treatments for depression. Our work starts from the observation that different depressed people respond to different treatments, and we work to identify the important differences in brain function and real-world behaviors that characterize an individual’s depressive illness. Once identified, we test whether the different patterns of brain and real-world functioning that we observe can serve as personalized treatment targets for the development of novel, individualized intervention strategies.

To accomplish these goals, we study individuals experiencing a broad range of mood and anxiety symptoms, as well as healthy people with no history of emotional or psychiatric problems. We use techniques from an array of disciplines, including functional magnetic resonance imaging (fMRI), clinical trials, personality and individual differences, longitudinal assessments of daily behaviors, and direct neuromodulation procedures that can alter the functioning of specific neural circuits in real time.


If you are interested in participating in any of our studies or in joining the lab, please contact us.